Abstract Objective: To compare the Rapid Shallow Breathing Index (RSBI) obtained by the ventilometer and from mechanical ventilation parameters. Methods: Randomized crossover trial, including 33 intubated patients, on mechanical ventilation for at least 24 hours, undergoing spontaneous breathing test. Patients were submitted to the measurement of RSBI by four methods: disconnected from the ventilator through the ventilometer; in Pressure Support Ventilation (PSV) mode at a pressure of 7 cm H2O; in Continuous Positive Airway Pressure (CPAP) mode at a pressure of 5 cmH2O with flow trigger; in CPAP mode at a pressure of 5 cmH2O with pressure trigger. Results: No significant difference was detected between the RSBI obtained by the ventilometer and in the CPAP mode with flow and pressure triggers, however, in the PSV mode, the values were lower than in the other measurements (p < 0.001). By selecting patients from the sample with higher RSBI (≥ 80 cycles.min−1.L−1), the value of the index obtained by the ventilometer was higher than that obtained in the three options of ventilation methods. Conclusion: The RSBI obtained in the CPAP mode at a pressure of 5 cmH2O, in both triggers types, did not differ from that measured by the ventilometer; it is, therefore, an alternative when obtaining it from mechanical ventilation parameters is necessary. However, in the presence of borderline values, the RSBI measured by ventilometer is recommended, as in this method the values are significantly higher than in the three ventilation modalities investigated.

RESUMO CONTEXTO: A cirrose hepática é uma doença altamente prevalente que, em estágio avançado, geralmente causa ascite e alterações respiratórias associadas. No entanto, existem poucos estudos avaliando e quantificando o impacto da ascite e do seu alívio através da paracentese na função pulmonar e em sintomas como fadiga e dispneia em pacientes cirróticos. OBJETIVO: Avaliar e quantificar o impacto da redução aguda do volume ascítico nos parâmetros respiratórios, sintomas de fadiga e dispneia em pacientes com cirrose hepática, bem como investigar possíveis correlações entre esses parâmetros. MÉTODOS: Trinta pacientes com cirrose hepática e ascite foram submetidos às seguintes avaliações pré e pós-paracentese: sinais vitais, padrão respiratório, mobilidade toracoabdominal (cirtometria), função pulmonar (ventilometria), grau de dispneia (escala numérica) e nível de fadiga (escala visual analógica). RESULTADOS: Houve maior prevalência de pacientes classificados como CHILD B e o escore MELD médio foi de 14,73±5,75. A comparação dos parâmetros pré e pós paracentese evidenciou após a paracentese: aumento do padrão respiratório predominantemente abdominal, melhora das variáveis ventilatórias, aumento das diferenças obtidas na cirtometria axilar e abdominal, redução do nível de dispneia e fadiga, redução da pressão arterial e aumento da saturação periférica de oxigênio. Correlações positivas encontradas: cirtometria xifoide com axilar, grau de dispneia com nível de fadiga, volume corrente com volume minuto, CHILD “C” com maior escore MELD, volume drenado na paracentese com maior escore MELD e com CHILD “C”. Também observamos uma correlação negativa entre volume corrente e a frequência respiratória. CONCLUSÃO: Uma vez que a drenagem da ascite em pacientes com cirrose hepática melhora os volumes pulmonares e a expansão torácica, além de reduzir sintomas como fadiga e dispneia, podemos concluir que a ascite tem um impacto respiratório e sintomatológico negativo nesses pacientes.

ABSTRACT BACKGROUND: Liver cirrhosis is a highly prevalent disease that, at an advanced stage, usually causes ascites and associated respiratory changes. However, there are few studies evaluating and quantifying the impact of ascites and its relief through paracentesis on lung function and symptoms such as fatigue and dyspnea in cirrhotic patients. OBJECTIVE: To assess and quantify the impact of acute reduction of ascitic volume on respiratory parameters, fatigue and dyspnea symptoms in patients with hepatic cirrhosis, as well as to investigate possible correlations between these parameters. METHODS: Thirty patients with hepatic cirrhosis and ascites who underwent the following pre and post paracentesis evaluations: vital signs, respiratory pattern, thoracoabdominal mobility (cirtometry), pulmonary function (ventilometry), degree of dyspnea (numerical scale) and fatigue level (visual analog scale). RESULTS: There was a higher prevalence of patients classified as CHILD B and the mean MELD score was 14.73±5.75. The comparison of pre and post paracentesis parameters evidenced after paracentesis: increase of predominantly abdominal breathing pattern, improvement of ventilatory variables, increase of the differences obtained in axillary and abdominal cirtometry, reduction of dyspnea and fatigue level, blood pressure reduction and increased peripheral oxygen saturation. Positive correlations found: xiphoid with axillary cirtometry, degree of dyspnea with fatigue level, tidal volume with minute volume, Child “C” with higher MELD score, volume drained in paracentesis with higher MELD score and with Child “C”. We also observed a negative correlation between tidal volume and respiratory rate. CONCLUSION: Since ascites drainage in patients with liver cirrhosis improves pulmonary volumes and thoracic expansion as well as reduces symptoms such as fatigue and dyspnea, we can conclude that ascites have a negative respiratory and symptomatological impact in these patients.

Resumo Introdução: A deterioração da função pulmonar é a principal causa de mortalidade na fibrose cística (FC), portanto é fundamental estudar diferentes fatores que se relacionam com esta variável. Objetivo: Verificar em indivíduos FC, a associação da função pulmonar com a mobilidade toracoabdominal e a postura. Método: Estudo piloto transversal realizado em indivíduos com FC (08-17 anos). A função pulmonar foi avaliada pela espirometria. A mobilidade toracoabdominal e a postura foram avaliadas por fotogrametria, usando o Software de Avaliação Postural (Sapo). Foi utilizado o Coeficiente de Correlação de Pearson, considerando-se significante p < 0,05. Resultados: As seguintes variáveis espirométricas apresentaram-se reduzidas em relação ao previsto: VEF 1, VEF 1 /FVC, PFE e FEF 25-75%. Na avaliação postural, foram observadas alterações no alinhamento horizontal da cabeça (AHC, 2,71 ± 2,23); alinhamento horizontal acrômios (AHA, 1,33 ± 1,35); alinhamento horizontal espinhas ilíacas ântero-superiores (AHEIAS, 1,11 ± 0,89); ângulo entre dois acrômios e duas espinhas ilíacas ântero-superiores (AEDAEDEIAS, 0,89º± 0,39); assimetria horizontal de escápula em relação a T3 (AHERT3, 16,95% ± 12,03); assimetria da projeção do centro de gravidade na base de sustentação no plano frontal (11,45 ± 8,10%) e sagital (48,98±18,55%). Foi encontrada correlação positiva forte entre função pulmonar e mobilidade toracoabdominal nas variáveis: distâncias anteroposterior do tórax superior (DAPTS) e FVC (r = 0,818; p = 0,024); DAPTS e VEF 1 (r = 0,874; p = 0,010); DAPTS e FEF 25-75% (r = 0,797; p = 0,032). Na correlação entre função pulmonar e postura houve correlação negativa forte entre VEF 1 /FVC e AHC (r = -0,761; p = 0.047). Conclusão: O estudo mostrou forte correlação positiva entre expansibilidade anteroposterior do tórax superior e função pulmonar, alta prevalência de cifoescoliose e forte correlação negativa entre AHC e função pulmonar.

Abstract Introduction: Deterioration of lung function is the main cause of mortality in cystic fibrosis (CF), so it is essential to study different related factors. Objective: To assess the association of pulmonary function with thoracoabdominal mobility and postural alignment in individuals with CF. Method: A cross-sectional study was performed in individuals with CF (8-17 years). Pulmonary function was assessed by spirometry. Thoracoabdominal mobility and postural alignment were evaluated by photogrammetry using the Postural Assessment Software (PAS/Sapo). Pearson correlation coefficient analysis was performed, and p < 0.05 was considered significant. Results: The following spirometric variables showed a decrease compared to predicted values: FEV1, FEV1/FVC, PEF and FEF25-75%. Postural assessment showed alterations in head horizontal alignment (HHA; 2.71 ± 2.23o), acromion horizontal alignment (AHA; 1.33 ± 1.35o), anterior superior iliac spine (ASIS) horizontal alignment (ASISHA; 1.11 ± 0.89o), angle between acromia and ASIS (AAASIS; 0.89 ± 0.39o), scapula horizontal asymmetry - T3 (SHAT3; 16.95 ± 12.03%), and asymmetry of the projection of the center of gravity within the base of support in the frontal (11.45 ± 8.10%) and sagittal (48.98 ± 18.55%) planes. A strong positive correlation was found between pulmonary function and thoracoabdominal mobility in the variables anteroposterior mobility of the upper chest (APMUC) and FVC (r = 0.818, p = 0.024), APMUC and FEV1 (r = 0.874, p = 0.010), and APMUC and FEF25-75% (r = 0.797, p = 0.032). A strong negative correlation was detected between FEV1/FVC and AHA (r = -0.761, p = 0.047). Conclusion: Our study showed in CF a reduction in pulmonary function, strong positive correlation between APMUC and pulmonary function, high prevalence of kyphoscoliosis and strong negative correlation between AHA and pulmonary function.

Resumen Introducción: El deterioro de la función pulmonar es la principal causa de mortalidad en la fibrosis quística (FQ) y es fundamental estudiar diferentes factores relacionados con esta variable. Objetivo: Verificar en individuos con FQ la asociación entre la función pulmonar, la movilidad toracoabdominal y la postura. Método: Estudio piloto transversal realizado en individuos con FQ (08-17 años). La función pulmonar fue evaluada por la espirometría. La movilidad toracoabdominal y la postura fueron evaluadas por fotogrametría, usando el Software de Evaluación Postural (Sapo). Se utilizó el Coeficiente de Correlación de Pearson, considerándose significante p < 0,05. Resultados: En la espirometría se encontraban menores que los valores previstos: VEF 1 , VEF 1 /CVF, PFE y FEF 25-75% . En la evaluación postural se observaron alteraciones en la alineación horizontal de la cabeza (AHC, 2,71 ± 2,23); alineación horizontal de los acromios (AHA, 1,33º± 1,35); alineación horizontal espinas ilíacas antero-superiores (AHEIAS, 1,11º± 0,89); ángulo entre dos acromios y dos espinas ilíacas antero-superiores (AEDAEDEIAS, 0,89 ± 0,39); asimetría horizontal de escápula con respecto a la T3 (AHERT3, 16,95% ± 12,03); asimetría de la proyección del centro de gravedad en la base de sustentación en el plano frontal (11,45±8,10%) y sagital (48,98±18,55%). Se encontró una correlación positiva fuerte entre la función pulmonar y la movilidad toracoabdominal en las variables: distancia anteroposterior del tórax superior (DAPTS) y CVF (r = 0,818; p = 0,024); DAPTS y VEF 1 (r = 0,874; p = 0,010); DAPTS y FEF 25-75% (r = 0,797; p = 0,032); y en la correlación entre la función pulmonar y la postura hubo una correlación negativa fuerte entre VEF 1 /CVF y AHC (r = -0,761; p = 0,047). Conclusión: El estudio mostró una fuerte correlación positiva entre la expansibilidad anteroposterior del tórax superior y la función pulmonar, alta prevalencia de cifoescoliosis y fuerte correlación negativa entre AHC y la función pulmonar.

ABSTRACT Objective This study was designed to identify the major musculoskeletal symptoms of individuals with obesity, to assess their health-related quality of life, and to evaluate the correlation between the musculoskeletal symptoms and the individuals’ health-related quality of life. Materials and methods Cross-sectional study. Instruments used “Nordic Musculoskeletal Questionnaire” and “The Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36)”. Results In total, 41 subjects were evaluated, of which 90.15% were female. The mean age of the subjects was 40.78 ± 9.85 years and their mean body-mass index was 46.87 ± 8.08. All subjects reported musculoskeletal pain in at least one anatomical region and 80.49% had pain in three or more regions. The activity limitations due to pain were reported by 75.61% of them. The most affected regions by pain were the ankles and/or feet, lower back, knees and wrists/hands/fingers. The most associated regions with activity limitations due to pain were the ankles and/or feet, knees and lower back. The presence of pain showed a negative correlation with the domains physical functioning (PF), role-physical (RP) and body pain (BP). The activity limitations showed a negative correlation with the domains PF, BP, social functioning (SF) and role-emotional (RE). Conclusion Our data showed a high prevalence of musculoskeletal pain and limitation in activities due to pain in obese subjects. The musculoskeletal symptoms had negative correlations with physical and mental components of the health-related quality of life, highlighting the importance of ensuring that patients with obesity have access to interdisciplinary care, for the prevention and rehabilitation of musculoskeletal disorders.